{"id":48,"date":"2022-11-11T09:54:42","date_gmt":"2022-11-11T14:54:42","guid":{"rendered":"https:\/\/dewpointx.com\/?page_id=48"},"modified":"2025-01-29T08:47:27","modified_gmt":"2025-01-29T13:47:27","slug":"pipeline","status":"publish","type":"page","link":"https:\/\/dewpointx.com\/pipeline\/","title":{"rendered":"Pipeline"},"content":{"rendered":"
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\nPartnering with the world\u2019s healthcare leaders\n<\/h2>
\nWe have discovery programs\u00a0across an ambitious pipeline and collaborations with leading global pharmaceutical partners.\n<\/div>\n<\/div><\/div>\n<\/section>
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\nPipeline\n<\/h1>

\nPrimary programs\n<\/h2>
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\nFrom the beginning, we recognized that with the breadth of therapeutic possibilities in condensate biology, exploring diseases on our own and with experienced partners would accelerate our growth and prove the value of this revolutionary approach.\n<\/div>\n<\/div>
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\nWe are partnering with the world\u2019s leading pharma companies to explore modulating condensates to target diseases across many therapeutic areas, while growing an ambitious pipeline of our own discovery programs.\n<\/div>\n<\/div><\/div>
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CRC = colorectal cancer; NSCLC = non-small cell lung cancer; TNBC = triple negative breast cancer<\/p>\n

See press releases for DPTX3186<\/a><\/b> and DPTX3496<\/a><\/b> development candidate nominations.<\/p>\n<\/div><\/div>\n<\/section>

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\nPartnerships\n<\/h2>
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Multi-year, multi-program research collaboration, option and license agreement addressing broad therapeutic area of cardiovascular diseases.  The partnership will leverage Dewpoint\u2019s proprietary platform for biomolecular condensates and Bayer\u2019s small molecule compound library and R&D capabilities to  identify and advance novel therapeutics.<\/p>\n<\/div>\n<\/div>\n<\/div>

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Research and development partnership to identify drug candidates using Dewpoint\u2019s discovery platform related to biomolecular condensates to treat insulin resistance. The partnership brings together Novo Nordisk\u2019s global leadership in treating diabetes and metabolic diseases with Dewpoint\u2019s groundbreaking discovery and AI technology platform to identify modulators of biomolecular condensates.<\/p>\n<\/div>\n<\/div>\n<\/div>

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\"evotec<\/div>\n\t<\/div><\/figure>\n\n<\/div>
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Strategic R&D collaboration to advance Dewpoint\u2019s leading oncology pipeline programs of condensate modifying therapeutics (c-mods) to Investigational New Drug Applications (\u201cINDs\u201d) using Evotec\u2019s industry-leading fully integrated data-driven platform (INDiGO).<\/p>\n<\/div>\n<\/div>\n<\/div>

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Partnership to develop a suite of digitally discovered and automatically synthesized novel molecules on Chemify\u2019s programmable chemistry platform against condensate targets of interest in Dewpoint\u2019s oncology and neurodegeneration pipeline.<\/p>\n<\/div>\n<\/div>\n<\/div>

\n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \n\n \n Read press release<\/span>\n\n \n \n <\/a>\n\n \n\n\n<\/div>\n<\/div>
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Collaboration to advance a small molecule condensate modulator (c-mod) targeting TDP-43, with the potential to address the underlying pathology of >97% of ALS patients. The partnership will leverage Dewpoint\u2019s platform and condensate science expertise and Mitsubishi Tanabe Pharma Corporation (MTPC)\u2019s unparalleled expertise in ALS therapeutic development. Upon achieving predetermined milestones, MTPC has an option for a global license to develop and commercialize the novel TDP-43 c-mod.<\/p>\n<\/div>\n<\/div>\n<\/div>

\n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \n\n \n Read press release<\/span>\n\n \n \n <\/a>\n\n \n\n\n<\/div>\n<\/div>
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Strategic partnership combining Concert AI\u2019s clinico-genomic data sets with Dewpoint\u2019s AI\/ML-powered discovery and development platform to optimize patient stratification for Dewpoint\u2019s oncology c-mod pipeline. The first phase of the partnership will drive development of the lead oncology program targeting beta catenin for Wnt-driven solid tumors.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>

\n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \n\n \n Read press release<\/span>\n\n \n \n <\/a>\n\n \n\n\n<\/div>\n<\/div><\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"

Partnering with the world\u2019s healthcare leaders We have discovery programs\u00a0across an ambitious pipeline and collaborations with leading global pharmaceutical partners. […]<\/p>\n","protected":false},"author":1,"featured_media":3339,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_breakdance_hide_in_design_set":false,"_breakdance_tags":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-48","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nPipeline | Dewpoint Therapeutics<\/title>\n<meta name=\"description\" content=\"Dewpoint has discovery programs across an ambitious pipeline and collaborations with leading global pharmaceutical partners.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dewpointx.com\/pipeline\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pipeline | Dewpoint Therapeutics\" 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